A semi - empirical model for transport of 10 inorganic nanoparticles across a lipid bilayer – 11 Implications for uptake by living cells . 12 13

A semi - empirical model for transport of 10 inorganic nanoparticles across a lipid bilayer – 11 Implications for uptake by living cells

A semi - empirical model for transport of 10 inorganic nanoparticles across a lipid bilayer – 11 Implications for uptake

A semi-empirical model for transport of inorganic nanoparticles across a lipid bilayer: implications for uptake by living cells.

Due to increasing application, release of nanoparticles (NPs) and nanomaterials into the environment becomes likely. Knowledge about NP uptake in organisms is crucial for risk assessment including estimations on the behavior of NPs based on their physicochemical properties. In the present study, the authors have applied current scientific knowledge to construct a mathematical model, which estim...

In-vitro cellular uptake and transport study of 9-nitrocamptothecin PLGA nanoparticles across Caco-2 cell monolayer model

The uptake and transport of 9-nitrocamptothecin (9-NC), a potent anticancer agent, across Caco-2 cell monolayers was studied as a free and PLGA nanoparticle loaded drug. Different sizes (110 to 950 nm) of 9-nitrocamptothecin nanoparticles using poly (lactic-glycolic acid) were prepared by via the nanoprecipitation method. The transport of nanoparticles across the Caco-2 cell monolayer as a func...

In-vitro cellular uptake and transport study of 9-nitrocamptothecin PLGA nanoparticles across Caco-2 cell monolayer model

The uptake and transport of 9-nitrocamptothecin (9-NC), a potent anticancer agent, across Caco-2 cell monolayers was studied as a free and PLGA nanoparticle loaded drug. Different sizes (110 to 950 nm) of 9-nitrocamptothecin nanoparticles using poly (lactic-glycolic acid) were prepared by via the nanoprecipitation method. The transport of nanoparticles across the Caco-2 cell monolayer as a func...